The BRCA1 cases included 25 individuals (ind) affected with breast cancer and 11 unaffected women, who were carriers of BRCA1 mutations namely R1443X (22 ind), 3705insA (2 ind), 2244insA (7 ind), 2953del3+C (2 ind) and three individuals carrying E352X, 4160delAG or 1723del9ins13 mutation, respectively. Here, BRCA1 is linked to breast cancer.