TPX2 and colorectal adenoma: A few example include amplification of the MYC oncogeneof 8q24 resulting in its over-expression, assuming a role a central driver in CRCs [14], the amplification of 20q, which has been reported causing mRNA overexpression of AURKA (20q13.2) and TPX2 (20q11), ultimately promoting progression from colorectal adenoma to carcinoma [13].