To illustrate this, as showed in Figure 2A, we first selected 8 unregulated genes located on 20q13.33 (YYHDF1), 20q13.32 (NELFCD or TH1L), 20q13.13 (STAU1), 20q13.12 (ZWIM3), 20q11.23 (AAR2 or C20orf4), 20q11.22 (PIGU) and 20q11.21 (PLAGL2 and POFUT1) for an additional somatic mutations analysis in CRC through cBioPortal (Colorectal Adenocarcinoma (TCGA, Provisional) 633 samples). Here, PLAGL2 is linked to colorectal adenocarcinoma.