Interestingly, further analysis of 3 genes (PLAGL2, POFUT1and STAU1) located on chromosome 20q and frequently unregulated in colorectal cancer exhibited significant co-expression levels (PLAGL2 vs. POFUT1, r=0.84, p<0.0001; POFUT1 vs.STAU1, r=0.66, p<0.0001), which prompted us to explore the co-expression of all genes located on 20q (Figure 3A). The gene discussed is PLAGL2; the disease is colorectal cancer.