TIPE1 and lung cancer: TIPE1 overexpression significantly prevented A549 lung cancer xenograft growth compared with the Ctrl control by approximately 65.8% in tumor volume (TIPE1 group: 538.27±67.21 mm3 versus Ctrl group: 1572.32±182.14 mm3; Figure 5A and 5B) and by approximately 68.4% in tumor weight (TIPE1 group: 0.49±0.04 g versus Ctrl group: 1.55±0.06 g; Figure 5C).