Treatment with chloroquine (25 μM, 5 h) increased OATP1B3 protein levels to 1.85 ± 0.3 (mean ± SD, n = 3; Fig 4A) and 1.49 ± 0.16 (mean ± SD, n = 3 donors; Fig 4B) fold of vehicle control in HEK293-OATP1B3 cells and human SCH, respectively. This evidence concerns the gene SLCO1B3 and spindle cell hemangioma.