KCNH2 and tuberculosis: Bedaquiline also shows inhibition of the hERG (human Ether-à-go-go-Related Gene; KCNH2) cardiac potassium channel, with the concomitant risk of delayed ventricular repolarization (QTc interval),6 and this is a point to be considered in the planning of combination regimens with other TB drugs with similar effects (e.g. fluoroquinolones, clofazimine).9