CD8A and lung adenocarcinoma: In lung adenocarcinoma with HLA LOH at all three loci, we observed an increase in abundance of CD8+ T cells and expression profiles associated with improved checkpoint blockade response (Herbst et al., 2014, Li et al., 2016, Piha-Paul et al., 2016, Ribas et al., 2015, Rooney et al., 2015, Tumeh et al., 2014).