In general, human tauopathies, which among others include progressive supranuclear palsy (PSP), Pick's disease, and corticobasal degeneration, display progressive accumulation of hyperphosphorylated microtubule‐associated protein tau and tau pathology together with behavioral impairments and loss in synaptic integrity without any Aβ deposits (Spillantini & Goedert, 2013; Wang & Mandelkow, 2016). The gene discussed is MAPT; the disease is tauopathy.