In somecases, DC vaccination can be combined with chemotherapy (gemcitabine for pancreatic tumor[65], cyclophosphamide for lymphocyticleukemia [73] and ovarian cancer[75], and docetaxel for prostate cancer[82]), with the application of other immunecells (e.g., cytokine-induced killer cells; i.e., T cells and natural killersactivated by IL-1, IL-2, IFN-γ and anti-CD3 antibodies for hepatic tumors[70]); tumor-infiltrating lymphocytesfor melanoma [76]), as well as withinjections of cytokines (GM-CSF for lymphocytic leukemia[73], IL-2 for osteosarcoma[74], and IFN-α-2b formelanoma [77]). This evidence concerns the gene IL2 and melanoma.