Recently, Martins and co-workers [145] have confirmed p27 underexpression in pituitary adenomas and have thus provided further evidence of the involvement of the post-translational machinery, although this phenomenon cannot be explained either by the mis-expression of p27 translational regulators DKC1, RPS13, miR221, and miR222 or by DKC1 mutations directly. The gene discussed is DKC1; the disease is pituitary gland adenoma.