CDKN2A and open-angle glaucoma: For the rs3088440-CDKN2A polymorphism, not statistically linked to the rs2157719-CDKN2B-AS1 polymorphism located in the region of chromosome 9p21 (CDKN2A/B) and widely studied for the association with POAG risk, the published results again have been population-specific [51,58,59,60].