LMNA and heart disorder: Over 400 LMNA mutations have been reported in patients with phenotypes known collectively as laminopathies including premature aging syndromes (Hutchinson–Gilford Progeria Syndrome and atypical Werner syndrome), skeletal muscle myopathies (Emery-Dreifuss Muscular Dystrophy and Limb-Girdle Muscular Dystrophy), and cardiac diseases (dilated cardiomyopathy and cardiac conduction defects) [11,18].