APOB and diabetes mellitus: In another study published by the SEARCH for Diabetes in Youth Case-Control (SEARCH CC) study, 512 children with T1DM with an average duration of diabetes of 4.2 years had higher small dense LDL particles (P < 0.001 for children with HbA1C ≥ 7.5%) and higher Apo-lipoprotein B (ApoB) (P < 0.0001) compared to 188 healthy controls [43].