Another pediatric study showed that 406 adolescents with T1DM with an average age of 14.1 ± 1.9 years and diabetes duration of 6.7 ± 3.7 years had evidence of early atherosclerosis based on aortic intima-media thickness when compared to 57 HC and that higher urinary albumin excretion, even within the normal range, was associated with early atherosclerosis in youth with T1DM [69]. The gene discussed is ALB; the disease is atherosclerosis.