Among the middle-aged men, pharmacy dispensing of ED medications was associated with a number of variables representing risk factors for ED such as pharmacy dispensing of antihypertensive medication, insulin, oral antidiabetics, lipid-modifying medications, anti-obesity medication, hypnotics, sedatives and antidepressants and having a diagnosis of diabetes or prostate cancer at a hospital discharge, Table 1. This evidence concerns the gene INS and diabetes mellitus.