TGFB1 and breast carcinoma: To further demonstrate the role and involvement of EPHA4 downstream of TGFβ- mediated cell migration in basal breast cancer, we infected MDA-MB-231 and SCP2 cells with lentiviruses overexpressing scrambled or EPHA4 shRNAs, in order to generate stable cells in which EPHA4 gene expression was specifically knockdown.