DNMT1 mRNA levels also correlated with the time- and concentration-dependent depletion of MYC in both T-ALL or Burkitt’s lymphoma-like cells; however, while DNMT3A mRNA levels followed the same trend in T-ALL, DNMT3A levels were less consistent with the titration of MYC in Burkitt’s lymphoma-like cells. Here, DNMT3A is linked to Burkitt lymphoma.