To determine whether DNMT1 and DNMT3B transcription in T-ALL and Burkitt’s lymphoma-like cells is directly regulated by oncogenic MYC, we performed chromatin immunoprecipitation (ChIP) analysis measuring MYC binding to the genomic loci of DNMT1, DNMT3A and DNMT3B. The gene discussed is DNMT1; the disease is acute lymphoblastic leukemia.