In T-ALL, DNMT1 was increased (1.54-fold, P=1.78×10-107), DNMT3A (3.03-fold, P=6.35×10-70) and DNMT3B (1.96-fold, P=1.95×10-34) compared to Peripheral Blood Mononuclear Cells (PBMCs). This evidence concerns the gene DNMT1 and acute lymphoblastic leukemia.