We found that in CML the MYC binding site upstream of DNMT1 exon 1 is enriched for the active chromatin marks H3K27Ac and H3K4Me3, as well as for H3K4Me1, which is associated with enhancer elements [33, 34]. The gene discussed is MYC; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.