DNMT3B and acute lymphoblastic leukemia: Treatment of non-malignant human embryonic kidney (HEK293T) cells, which don’t express detectable levels of DNMT3B, with NA led to a significant, but less drastic reduction in cell proliferation (25nM NA reduced T-ALL proliferation by 31.1%, while affecting HEK293T cells by 17.5%) (Supplementary Figure 6).