Co-expression analysis indicated that ITGA5 mRNA expression had a significantly positive correlation with ITGB5 (r=0.32, P<0.001) in tumor tissue, whereas ITGA2B had a significantly negative correlation with ITGA5 (r=-0.142, P =0.035) and ITGB5 (r=-0.34, P <0.001), respectively. This evidence concerns the gene ITGB5 and neoplasm.