Image analysis showed that in the tumours there was increased immunoreactivity for PGP9.5 (Figure 1I, 1J; nerve number/field of view; Normal = 0.46 ± 0.25; Tumour = 1.25 ± 0.23) and CGRP (Figure 1K, 1L; nerve number/field of view; Normal = 0.29 ± 0.13; Tumour = 1.29 ± 0.41) compared to non-tumour bearing mice. This evidence concerns the gene UCHL1 and neoplasm.