Analysis of p53 at codon 72 for the status of variant forms by genotyping revealed a higher frequency of Arg/Pro phenotypes (18/34, 53%) than Arg/Arg (9 of 34, 26%) or Pro/Pro (7 of 34, 21%) in these CRC; however, in this study homozygous Pro/Pro was observed more frequency compared to other previous studies (data not shown). This evidence concerns the gene TP53 and colorectal carcinoma.