BUB1 and gastric cancer: In addition to poor survival, patients with GC showing low BUB1 expression had a significantly higher tumor stage (p < 0.001), higher rates of lymph node metastases (p = 0.027) and distant metastases (p = 0.006) and a significantly higher UICC stage (p < 0.001), which may be another reason for the poor survival in this group and may suggest closer clinical follow up of patients, whose tumors show low BUB1 expression.