By using our HRMA platform, we have successfully genotyped the 5 SNPs including rs12343867 (JAK2 46/1 haplotype), JAK2 rs12339666, TERT rs2736100, MECOM rs2201862 and HBS1L-MYB rs9376092 in more than 95% of samples from MPN patients (Figure 1). The gene discussed is JAK2; the disease is myeloproliferative neoplasm.