In disease subtype comparison, the MAF of JAK2 rs12343867 and JAK2 rs12339666 was significantly higher in PV than ET, and the MAF of MECOM rs2201862 was significantly higher in MF than PV when all MPNs were included (Table 3) and also in JAK2V617F-positive cases (Table 4). This evidence concerns the gene JAK2 and essential thrombocythemia.