Based on the above observations and the typical plasma concentrations (5 to 50 nM) of AML [17,37], its enantiomers can be regarded as weak to moderate inhibitors of CYP2C9 and CYP2C19 that exhibit stereoselective patterns only under special conditions (drug accumulation, overdosing, etc.). This evidence concerns the gene CYP2C9 and acute myeloid leukemia.