AVP and Central diabetes insipidus: Using IF on unfixed tissue samples of human (from both fetal and adults) and baboon hypothalamus, AHAs to ADH cells (titer: 1:1–32) were reported in adult patients affected by diabetes insipidus, in both idiopathic (11 out of 30) and symptomatic (2 out of 32) cases, but in none of the controls (n = 139) [38].