Thehigh-impact, most prevalent conditions in our study (Carrier Map group) were:21-Hydroxilase-Deficient Congenital Nonclassical Adrenal Hyperplasia (1/8),Factor V deficiency (1/12), Hemochromatosis: Type 1: HFE Related (1/12), ShortChain Acyl-CoA (1/14) and MTHFR deficiency (1/3) (39%). This evidence concerns the gene MTHFR and hyperinsulinemic hypoglycemia, familial, 4.