GPT and hepatocellular carcinoma: In the work reported by Taura et al. [28], on the analysis of the liver enzyme activity in 200 HBsAg-seropositive patients, 17.0% were seropositive for HBeAg with elevated serum level of ALT and 44.8% of the HBeAg-infected subjects had ongoing liver damage, with 5% linked to HCC.