In our current study, we report direct relationships among the concentrations and composition of several SaFAs among “free”, “total”, and LPC molecules and markers of immune activation and inflammation (including IL-6, sCD14, D-dimer, TNFR-1) that are predictive of morbidity and mortality in HIV infection [39, , –42]. The gene discussed is TNFRSF1A; the disease is HIV infectious disease.