After controlling for age and infection at time of sampling (PCR and/or blood smear positive infection), higher frequencies of Pf-specific monofunctional IL10 CD4 T cells were associated with a decreased odds of symptoms, given patent infection (adjusted OR 0.66 95% CI 0.43–0.99, p = 0.05, Figure 5B; Table S4 in Supplementary Material. This evidence concerns the gene IL10 and infection.