In contrast, the proportion of cells producing IFNγ without IL10 was associated with a trend to increased prospective risk of infection in univariate analysis, but this was not significant following adjustment for dMER and other covariates (OR 1.01 for a 1% increase in IFNγ production in the absence of IL10, p = 0.06, Table S3 in Supplementary Material). The gene discussed is IL10; the disease is infection.