The 17-AAG-treated tumors also exhibited significantly fewer Ki67-positive proliferating cells (Figure 6(a)), which was consistent with delayed tumor growth (2.22 ± 0.34-fold volume increase over tumor volume measure immediately before treatment for the 17-AAG-treated mice versus 3.90 ± 0.37 for the vehicle-treated ones, P < 0.01; Figure 6(b)). The gene discussed is MKI67; the disease is neoplasm.