Although the levels of COL1A1 mRNA expression at 28 days after starting BLM administration were not lower in the BLM-plus-mAdSCs (2.5 × 104) group, they were significantly lower in the BLM-plus-mAdSCs (2.5 × 105) group than those in the BLM-alone group (Fig. 3d). This evidence concerns the gene COL1A1 and Bloom syndrome.