We found that silencing WDR7-7 with specific shRNAs increased GPR30 levels in both ER+ (MCF-7, T47D) and ER− breast cancer cells (SKBR3, MDA-MB-468), contributing to the promotion of cell growth (p < 0.05; Fig. 4a-b, g-h). The gene discussed is GPER1; the disease is breast cancer.