MAPT and supranuclear palsy, progressive, 1: In the context of atypical parkinsonian disorders, progressive supranuclear palsy (PSP), Steele–Richardson–Olszewsky syndrome (SR) type, belongs to the family of tauopathies, as it involves the accumulation of abnormally phosphorylated tau protein in both neurons and glia of cortical and subcortical structures [10].