GALNS and Stroke: Axonal remodeling in the brainstem-spinal pathways has been reported in spontaneous recovery after spinal cord injury [34] and stroke [10], and axonal remodeling in these pathways can be promoted by combined treatment with chondroitinase ABC injection and rehabilitative training [35], as well as by genetic ablation of the Nogo receptor 1 [34], indicating intrinsic axonal plasticity in brainstem-spinal pathways.