The impaired healing of gastric ulcer in diabetic rats was associated with suppressed tissue expression endothelial cell markers (i.e. eNOS and peNOS), enhanced pro-inflammatory reactions (i.e. IL-1β, IL-6 and myeloperoxidase activity, S2 and S4 Figs) and reduced regenerative activity (i.e. MMP-2, IL-10 and cAMP, S3 and S4 Figs). Here, IL10 is linked to gastric ulcer.