To learn if the intracellular survival signaling was stimulated by MΦ/MM co-culture that conferred bort resistance of MM cells in vitro, first, apoptotic cell characteristics of PARP and caspase-3 cleavage were detected using western blot in MM cells under co-culture conditions either with BAFF-neutralizing antibody or control IgG2B in the presence of bort. Here, CASP3 is linked to Miyoshi myopathy.