It also enhances the survival of various B lymphocyte malignancies, including MM.12, 13, 14 It can act as a membrane-bound or proteolytically cleaved soluble form displaying typical features of type II transmembrane protein.15It is expressed predominantly by stromal compartment including osteoclast, MΦs, dendritic cells, and some T cells.16 Some studies have found that the tumor microenvironment secretes BAFF.17 Here, TNFSF13B is linked to neoplasm.