The treatment with aspirin (acetylsalicylic acid), an anti-inflammatory drug, enhances LXA4 production, which in turn suppresses neutrophil migration and TNF-α production, thereby regulating inflammatory pathology during mycobacterial infection, as has been suggested for tuberculous meningitis (TBM) (24, 55) (Table 1). This evidence concerns the gene TNF and meningeal tuberculosis.