Among patients with anti-LGI1 encephalitis, hypothalamic dysfunction in form of hyponatremia due to the syndrome of inappropriate antidiuretic hormone secretion [~60% of patients (5, 6)] and basal ganglia involvement in form of faciobrachial dystonic seizures [~50% of patients (8)] are readily known. The gene discussed is LGI1; the disease is Hyponatremia.