Recently, 2 patients with sagittal craniosynostosis and clinical manifestations consistent with the Lin-Gettig syndrome phenotype have been described as carriers of de novo frameshift mutations in KAT6B. Interestingly, both patients had features overlapping those of SBBYSS and GTPTS (Bashir et al., 2017), suggesting that Lin-Gettig syndrome is in the spectrum of KAT6B-related disorders as well. This evidence concerns the gene KAT6B and craniosynostosis.