Other genes with roles in the same morphogenic events regulated by the FGFR family have been described in craniosynostosis, including TWIST1 (TWIST family bHLH transcription factor 1; *601622), EFNB1(Ephrin B1; *300035), POR (Cytochrome P450 oxidoreductase; *124015), RAB23 (RAS-associated protein RAB23; *606144), and EFNA4 (Ephrin A4; *601380) (Merrill et al., 2006; Wilkie et al., 2007; Melville et al., 2010; Jezela-Stanek and Krajewska-Walasek, 2013). This evidence concerns the gene EFNA4 and craniosynostosis.