A previous study reported that the genetic risk score was reported to be cross-sectionally associated with the risk of having IGT but not IFG using nine genes (FTO, HHEX, KCNJ11, KCNQ1, MTNR1B, PPARG, SLC30A8, TCF7L2, WFS1), which were established to be major loci associated with the risk of T2DM.73 When applying this finding to this meta-analysis, seven of these nine genes were ranked in the top 10 genes that frequently appeared in the included studies in this meta-analysis. Here, HHEX is linked to type 2 diabetes mellitus.