Strong to moderate positive correlation was observed between PDCD4 and DFFA in esophageal cancer tissues (r = 0.657, P = 0.039), and between PDCD4 and ANXA1 in gastric carcinoma (r = 0.683, P = 0.007) and colorectal cancer (r = 0.617, P = 0.001) (Fig 5). The gene discussed is ANXA1; the disease is esophageal cancer.