EGFR is a type-I transmembrane glycoprotein, which is similar to the platelet aggregation-inducing factor podoplanin.(15) We previously produced anti-podoplanin cancer-specific mAbs (CasMabs), clones LpMab-2(16,17) and LpMab-23,(18,19) which particularly recognized cancer-type podoplanin. The gene discussed is PDPN; the disease is cancer.