A similar pattern of cell viability inhibition in response to CHL1 knockdown was observed in both SHG44 glioma and U-87 MG glioblastoma cells, with remarkable viability inhibition observed at both 72 h and 96 h time points (p < 0.01 vs. controls at both time points; Figure 3). The gene discussed is CHL1; the disease is central nervous system cancer.