MTOR and cancer: When Method Two is used to assess mixed tendon tissues as well as TET and Achilles tendon separately, pathway and gene ontology analyses identify age-related decreases in glycosylation, and immune responses alongside increases in fcγ R-mediated phagocytosis, RIG-I like receptor signalling, mTOR signalling, PPAR signalling, and pathways in cancer (Tables M2S4 and M2S5, Figures M2S18–M2S26).