ABRAXAS1 and neoplasm: Interestingly, the same peak region of homozygous deletions also contains FAM175A (also called ABRAXAS), a suggested tumour suppressor gene that encodes a protein component of the BRCA1–A complex that leads the BRCA1-BARD1 heterodimer to sites of DNA double-strand breaks, targeting these for homologous recombination43,44.