In a subgroup analysis of cancers type,significant association was found between high expression levels of CCAT2 and OS in the digestive system cancers(HR: 1.57, 95%CI: 1.14-2.17, P=0.006) and urogenital system cancer patients (HR=2.74,95% CI: 1.98–3.80, p<0.0001).The association between CCAT2 and OS was significant in studies with sample size both fewer than 100 (HR:2.58, 95%CI: 1.77-3.77, P<0.001) and more than 100 (HR:1.87,95%CI:1.46-2.40,P<0.001).And there was no significant heterogeneity in this subgroup annalysis. Here, CCAT2 is linked to digestive system cancer.