Summary receiver operator characteristic (SROC) curve was constructed based on the sensitivity and specificity of eligible studies, it’s corresponding area under the SROC curve (AUC) was 0.99 (0.98–1.00) (Figure 6), which suggested that PCR had a relatively high diagnostic performance in detecting ALK gene rearrangement of NSCLC patients. Here, ALK is linked to non-small cell lung carcinoma.