The meta-analysis of all these studies showed that there were no significant association between FoxP3+ Tregs and 1, 3, 5-year DFS (OR = 1.36, 95% CI = 0.43 to 4.34, P = 0.604; OR = 1.55, 95% CI = 0.61 to 3.93, P = 0.353 and OR = 1.23, 95% CI = 0.38 to 4.01, P = 0.731 respectively) of CRC patients. The gene discussed is FOXP3; the disease is colorectal carcinoma.