ALB and metastatic malignant neoplasm in the lymph nodes: We compared the high groups and low groups for these indicators and increased Fib, FPR and deceased Alb, pAlb and AFR were positively correlated with age (more than 60 years), tumor size (larger than 5cm), tumor stage (III), depth of invasion depth (T3-T4), lymph node metastasis (N1-N3) and poor OS (all P<0.001) (Table 2 and Figure 2).