PTTG1 and ovarian neoplasm: In our recent studies, we showed that securin is co-expressed with various CSCs markers (CD24, CD34, CD44, CD117, CD133, ALDH1, SSEA4, Oct4, Shh, beta-catenin and LGR5) in normal ovary (NO), benign (BN), borderline (BL) and high grade (HG) ovarian tumors (unpublished observations), suggesting an important role of securin in modulating the CSC population.