A recent research analyzing FAM83D-coexpressed genes in various tumor types was performed using the Oncomine cancer microarray database, of which, 150 genes were strongly linked with cell cycle and mitosis based on pathway function enrichment, including AURKA, AURKB, CCNA2, CCNB1-2, CDC20, CDC25A-C, HMMR, PLK1, TPX2 [35]. The gene discussed is PLK1; the disease is cancer.