Additionally, the age of the patients in the de-novo stage (Odds ratio 1 CI (0.7-1.2) p>0.05), IDH1/2 mutation status (Odds ratio 0.8 CI (0.3-1.2) p>0.05) was not associated with a lower PD-L1 expression in the recurrent tumour. The gene discussed is IDH1; the disease is neoplasm.