TSHR and cancer: In this study, our further analysis revealed that PTC patients’ preoperative PB TSHR mRNA expression level was associated with age, histological type, capsular invasion status, lymph node metastasis status, and BRAFV600E mutation status (P < 0.05) but not gender, tumor size, number of cancer foci, or HT status (P > 0.05) (Table 1).